American Airlines flight AA 5181: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Daily 06:00 Daytona Beach (DAB) 07:48 Charlotte (CLT)
AA 5181 Non-stop Canadair CRJ 900 (CR9) 1:48 Effective 2025-05-05 through 2025-06-04
Daily 08:00 Chicago O'Hare (ORD) 3 10:44 Knoxville (TYS)
AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:44 Effective 2026-01-07 through 2026-02-11
Mon-Fri,Sun 10:16 Ronald Reagan Washington (DCA) 2 11:52 Cleveland Hopkins (CLE)
AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:36 Valid until 2025-05-04
Sat 12:38 Ronald Reagan Washington (DCA) 2 14:02 Cleveland Hopkins (CLE)
AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:24 Valid until 2025-05-03
Daily 13:26 Knoxville (TYS) 14:20 Chicago O'Hare (ORD) 3
AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:54 Effective 2026-01-07 through 2026-02-11
Daily 14:50 Chicago O'Hare (ORD) 3 17:28 Knoxville (TYS)
AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:38 Effective 2025-11-02 through 2025-12-02
Fri 15:12 Chicago O'Hare (ORD) 3 17:58 Greenville/Spartanburg (GSP)
AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:46 Operates only on 2025-07-04
Daily 17:57 Ronald Reagan Washington (DCA) 2 19:19 Hartford (BDL)
AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:22 Effective 2025-10-06 through 2025-10-25
Daily 18:05 Charlotte (CLT) 19:28 Savannah (SAV)
AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:23 Effective 2025-09-03 through 2025-10-05
Daily 18:05 Charlotte (CLT) 19:21 Savannah (SAV)
AA 5181 Non-stop Canadair CRJ 900 (CR9) 1:16 Effective 2025-10-26 through 2025-11-01
Daily 18:05 Charlotte (CLT) 19:25 Savannah (SAV)
AA 5181 Non-stop Canadair CRJ 900 (CR9) 1:20 Effective 2025-12-18 through 2026-01-05
Tue 18:05 Charlotte (CLT) 19:24 Savannah (SAV)
AA 5181 Non-stop Canadair CRJ 900 (CR9) 1:19 Operates only on 2026-01-06
Daily 18:05 Charlotte (CLT) 19:19 Savannah (SAV)
AA 5181 Non-stop Canadair CRJ 900 (CR9) 1:14 Effective from 2026-02-12
Daily 18:30 Philadelphia (PHL) F 20:48 Louisville (SDF)
AA 5181 Non-stop Canadair CRJ 700 (CR7) 2:18 Effective 2025-08-06 through 2025-09-02
Fri 18:35 Chicago O'Hare (ORD) 3 21:36 Greenville/Spartanburg (GSP)
AA 5181 Non-stop Canadair CRJ 700 (CR7) 2:01 Effective 2025-07-11 through 2025-08-01
Daily 18:35 Philadelphia (PHL) F 20:45 Lexington (LEX)
AA 5181 Non-stop Canadair CRJ 700 (CR7) 2:10 Effective 2025-12-03 through 2025-12-17
Mon-Thu,Sat 18:40 Chicago O'Hare (ORD) 3 21:40 Greenville/Spartanburg (GSP)
AA 5181 Non-stop Canadair CRJ 700 (CR7) 2:00 Effective 2025-07-05 through 2025-08-05
Mon-Sat 18:50 Chicago O'Hare (ORD) 3 21:43 Greenville/Spartanburg (GSP)
AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:53 Effective 2025-06-05 through 2025-07-03
Daily 18:54 Knoxville (TYS) 19:50 Chicago O'Hare (ORD) 3
AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:56 Effective 2025-11-02 through 2025-12-02
Sun 18:55 Chicago O'Hare (ORD) 3 21:48 Greenville/Spartanburg (GSP)
AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:53 Effective 2025-06-08 through 2025-06-29
Sun 18:56 Chicago O'Hare (ORD) 3 21:53 Greenville/Spartanburg (GSP)
AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:57 Effective 2025-07-06 through 2025-08-03
Daily 20:01 Hartford (BDL) 21:30 Ronald Reagan Washington (DCA) 2
AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:29 Effective 2025-10-06 through 2025-10-25
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This flight number is listed as serving the following routes:


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American Airlines flight AA 5181: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA5181
06:00
Daytona Beach (DAB)

07:48
Charlotte (CLT)
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:48, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5181
08:00
Chicago O'Hare (ORD) 3

10:44
Knoxville (TYS)
Effective 2026-01-07 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:44, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
10:16
Ronald Reagan Washington (DCA) 2

11:52
Cleveland Hopkins (CLE)
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:36, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
12:38
Ronald Reagan Washington (DCA) 2

14:02
Cleveland Hopkins (CLE)
Valid until 2025-05-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:24, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
13:26
Knoxville (TYS)

14:20
Chicago O'Hare (ORD) 3
Effective 2026-01-07 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:54, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
14:50
Chicago O'Hare (ORD) 3

17:28
Knoxville (TYS)
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:38, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
15:12
Chicago O'Hare (ORD) 3

17:58
Greenville/Spartanburg (GSP)
Operates only on 2025-07-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 1:46, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
17:57
Ronald Reagan Washington (DCA) 2

19:19
Hartford (BDL)
Effective 2025-10-06 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:22, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
18:05
Charlotte (CLT)

19:28
Savannah (SAV)
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:23, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
18:05
Charlotte (CLT)

19:21
Savannah (SAV)
Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:16, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5181
18:05
Charlotte (CLT)

19:25
Savannah (SAV)
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:20, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5181
18:05
Charlotte (CLT)

19:24
Savannah (SAV)
Operates only on 2026-01-06
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:19, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5181
18:05
Charlotte (CLT)

19:19
Savannah (SAV)
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:14, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5181
18:30
Philadelphia (PHL) F

20:48
Louisville (SDF)
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:18, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
18:35
Chicago O'Hare (ORD) 3

21:36
Greenville/Spartanburg (GSP)
Effective 2025-07-11 through 2025-08-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:01, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
18:35
Philadelphia (PHL) F

20:45
Lexington (LEX)
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:10, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
18:40
Chicago O'Hare (ORD) 3

21:40
Greenville/Spartanburg (GSP)
Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
-
Sat
Sun
-
Duration: 2:00, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
18:50
Chicago O'Hare (ORD) 3

21:43
Greenville/Spartanburg (GSP)
Effective 2025-06-05 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Duration: 1:53, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
18:54
Knoxville (TYS)

19:50
Chicago O'Hare (ORD) 3
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:56, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
18:55
Chicago O'Hare (ORD) 3

21:48
Greenville/Spartanburg (GSP)
Effective 2025-06-08 through 2025-06-29
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:53, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
18:56
Chicago O'Hare (ORD) 3

21:53
Greenville/Spartanburg (GSP)
Effective 2025-07-06 through 2025-08-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:57, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5181
20:01
Hartford (BDL)

21:30
Ronald Reagan Washington (DCA) 2
Effective 2025-10-06 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:29, non-stop
Canadair CRJ 700 (CR7)
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This flight number is listed as serving the following routes:
  • Charlotte (CLT) - Savannah (SAV)
  • Chicago O'Hare (ORD) - Greenville/Spartanburg (GSP)
  • Daytona Beach (DAB) - Charlotte (CLT)
  • Knoxville (TYS) - Chicago O'Hare (ORD)
  • Philadelphia (PHL) - Lexington (LEX)
  • Philadelphia (PHL) - Louisville (SDF)
  • Ronald Reagan Washington (DCA) - Cleveland Hopkins (CLE)
  • Ronald Reagan Washington (DCA) - Hartford (BDL)
All American Airlines flights
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