Alaska Airlines flight AS 4452: Multiple routes

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FLIGHT SCHEDULE
Direct Codeshare Flights:
Daily 01:00 Phoenix Sky Harbor (PHX) 4 07:00 Ronald Reagan Washington (DCA) 2
AS 4452 Non-stop Airbus A321neo (32Q) 4:00 Effective from 2026-02-12
Codeshare flight, operated by American Airlines.(AA 1640)
Daily 08:38 Dayton (DAY) 09:10 Chicago O'Hare (ORD) 3
AS 4452 Non-stop Canadair CRJ 700 (CR7) 1:32 Effective 2025-12-18 through 2026-01-05
Codeshare flight, operated by American Airlines.(AA 5210)
Daily 08:45 Phoenix Sky Harbor (PHX) 4 13:53 Des Moines (DSM)
AS 4452 Non-stop Embraer EMB 175 (E75) 3:08 Effective 2025-07-05 through 2025-08-05
Codeshare flight, operated by American Airlines.(AA 6244)
Daily 10:31 Destin/Fort Walton Beach (VPS) 13:48 Ronald Reagan Washington (DCA) 2
AS 4452 Non-stop Canadair CRJ 700 (CR7) 2:17 Effective 2025-10-06 through 2025-11-01
Codeshare flight, operated by American Airlines.(AA 5462)
Daily 10:40 Destin/Fort Walton Beach (VPS) 13:58 Ronald Reagan Washington (DCA) 2
AS 4452 Non-stop Canadair CRJ 700 (CR7) 2:18 Effective 2026-01-06 through 2026-02-11
Codeshare flight, operated by American Airlines.(AA 5462)
Daily 10:42 Destin/Fort Walton Beach (VPS) 13:59 Ronald Reagan Washington (DCA) 2
AS 4452 Non-stop Canadair CRJ 700 (CR7) 2:17 Effective 2025-09-03 through 2025-10-05
Codeshare flight, operated by American Airlines.(AA 5462)
Daily 11:07 Destin/Fort Walton Beach (VPS) 14:24 Ronald Reagan Washington (DCA) 2
AS 4452 Non-stop Canadair CRJ 700 (CR7) 2:17 Effective 2025-12-03 through 2025-12-17
Codeshare flight, operated by American Airlines.(AA 5462)
Daily 11:14 Destin/Fort Walton Beach (VPS) 14:24 Ronald Reagan Washington (DCA) 2
AS 4452 Non-stop Embraer EMB 175 (E75) 2:10 Effective 2025-11-02 through 2025-12-02
Codeshare flight, operated by American Airlines.(AA 4473)
Sat 11:43 Destin/Fort Walton Beach (VPS) 15:05 Ronald Reagan Washington (DCA) 2
AS 4452 Non-stop Canadair CRJ 700 (CR7) 2:22 Effective 2025-06-14 through 2025-06-28
Codeshare flight, operated by American Airlines.(AA 5617)
Mon-Fri 13:31 Chicago O'Hare (ORD) 3 15:06 Nashville (BNA)
AS 4452 Non-stop Canadair CRJ 700 (CR7) 1:35 Effective 2025-05-05 through 2025-05-09
Codeshare flight, operated by American Airlines.(AA 6346)
Daily 14:23 Des Moines (DSM) 15:26 Phoenix Sky Harbor (PHX) 4
AS 4452 Non-stop Embraer EMB 175 (E75) 3:03 Effective 2025-07-05 through 2025-08-05
Codeshare flight, operated by American Airlines.(AA 6244)
Wed,Sun 14:55 Chicago O'Hare (ORD) 3 16:27 Kansas City (MCI)
AS 4452 Non-stop Airbus A319 (319) 1:32 Effective 2025-06-15 through 2025-07-02
Codeshare flight, operated by American Airlines.(AA 3130)
Sat 15:58 Charleston (CHS) 17:53 Philadelphia (PHL)
AS 4452 Non-stop Embraer EMB 175 (E75) 1:55 Valid until 2025-05-03
Codeshare flight, operated by American Airlines.(AA 4407)
Sun 18:55 Phoenix Sky Harbor (PHX) 4 23:30 George Bush, Houston (IAH) A
AS 4452 Non-stop Embraer EMB 175 (E75) 2:35 Operates only on 2025-05-04
Codeshare flight, operated by American Airlines.(AA 3682)
Daily 20:15 Richmond (RIC) 21:30 Chicago O'Hare (ORD) 3
AS 4452 Non-stop Canadair CRJ 700 (CR7) 2:15 Effective 2025-08-06 through 2025-09-02
Codeshare flight, operated by American Airlines.(AA 4933)
Daily 20:25 Chicago O'Hare (ORD) 3 23:15 Toronto Pearson (YYZ) 3
AS 4452 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:50 Effective 2025-05-10 through 2025-05-23
Codeshare flight, operated by American Airlines.(AA 3456)
Daily 20:25 Chicago O'Hare (ORD) 3 23:15 Toronto Pearson (YYZ) 3
AS 4452 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:50 Effective 2025-05-25 through 2025-06-04
Codeshare flight, operated by American Airlines.(AA 3456)
Daily 20:30 Ronald Reagan Washington (DCA) 2 21:36 Pittsburgh (PIT)
AS 4452 Non-stop Embraer EMB 175 (E75) 1:06 Effective 2025-06-05 through 2025-06-13
Codeshare flight, operated by American Airlines.(AA 4763)
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This flight number is listed as serving the following routes:


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Alaska Airlines flight AS 4452: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Alaska Airlines AS4452
01:00
Phoenix Sky Harbor (PHX) 4

07:00
Ronald Reagan Washington (DCA) 2
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 1640)
Duration: 4:00, non-stop
Airbus A321neo (32Q)
Alaska Airlines AS4452
08:38
Dayton (DAY)

09:10
Chicago O'Hare (ORD) 3
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5210)
Duration: 1:32, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4452
08:45
Phoenix Sky Harbor (PHX) 4

13:53
Des Moines (DSM)
Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6244)
Duration: 3:08, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4452
10:31
Destin/Fort Walton Beach (VPS)

13:48
Ronald Reagan Washington (DCA) 2
Effective 2025-10-06 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5462)
Duration: 2:17, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4452
10:40
Destin/Fort Walton Beach (VPS)

13:58
Ronald Reagan Washington (DCA) 2
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5462)
Duration: 2:18, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4452
10:42
Destin/Fort Walton Beach (VPS)

13:59
Ronald Reagan Washington (DCA) 2
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5462)
Duration: 2:17, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4452
11:07
Destin/Fort Walton Beach (VPS)

14:24
Ronald Reagan Washington (DCA) 2
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5462)
Duration: 2:17, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4452
11:14
Destin/Fort Walton Beach (VPS)

14:24
Ronald Reagan Washington (DCA) 2
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4473)
Duration: 2:10, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4452
11:43
Destin/Fort Walton Beach (VPS)

15:05
Ronald Reagan Washington (DCA) 2
Effective 2025-06-14 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 5617)
Duration: 2:22, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4452
13:31
Chicago O'Hare (ORD) 3

15:06
Nashville (BNA)
Effective 2025-05-05 through 2025-05-09
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 6346)
Duration: 1:35, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4452
14:23
Des Moines (DSM)

15:26
Phoenix Sky Harbor (PHX) 4
Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6244)
Duration: 3:03, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4452
14:55
Chicago O'Hare (ORD) 3

16:27
Kansas City (MCI)
Effective 2025-06-15 through 2025-07-02
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 3130)
Duration: 1:32, non-stop
Airbus A319 (319)
Alaska Airlines AS4452
15:58
Charleston (CHS)

17:53
Philadelphia (PHL)
Valid until 2025-05-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 4407)
Duration: 1:55, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4452
18:55
Phoenix Sky Harbor (PHX) 4

23:30
George Bush, Houston (IAH) A
Operates only on 2025-05-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 3682)
Duration: 2:35, non-stop
Embraer EMB 175 (E75)
Alaska Airlines AS4452
20:15
Richmond (RIC)

21:30
Chicago O'Hare (ORD) 3
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4933)
Duration: 2:15, non-stop
Canadair CRJ 700 (CR7)
Alaska Airlines AS4452
20:25
Chicago O'Hare (ORD) 3

23:15
Toronto Pearson (YYZ) 3
Effective 2025-05-10 through 2025-05-23
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3456)
Duration: 1:50, non-stop
Embraer EMB 170 / EMB 175 (E70)
Alaska Airlines AS4452
20:25
Chicago O'Hare (ORD) 3

23:15
Toronto Pearson (YYZ) 3
Effective 2025-05-25 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3456)
Duration: 1:50, non-stop
Embraer EMB 170 / EMB 175 (E70)
Alaska Airlines AS4452
20:30
Ronald Reagan Washington (DCA) 2

21:36
Pittsburgh (PIT)
Effective 2025-06-05 through 2025-06-13
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 4763)
Duration: 1:06, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Charleston (CHS) - Philadelphia (PHL)
  • Chicago O'Hare (ORD) - Kansas City (MCI)
  • Chicago O'Hare (ORD) - Nashville (BNA)
  • Chicago O'Hare (ORD) - Toronto Pearson (YYZ)
  • Dayton (DAY) - Chicago O'Hare (ORD)
  • Destin/Fort Walton Beach (VPS) - Ronald Reagan Washington (DCA)
  • Phoenix Sky Harbor (PHX) - Des Moines (DSM)
  • Phoenix Sky Harbor (PHX) - George Bush, Houston (IAH)
  • Phoenix Sky Harbor (PHX) - Ronald Reagan Washington (DCA)
  • Richmond (RIC) - Chicago O'Hare (ORD)
  • Ronald Reagan Washington (DCA) - Pittsburgh (PIT)
All Alaska Airlines flights
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